Bananas are quite a magical fruit and they’ve been used for everything from “vegan leather” for wallets to durable bioplastics and feedstock. Now, scientists have found yet another use for this versatile edible: cancer detection. As first reported by the Huffington Post, researchers at the Ecole Polytechnique Federale de Lausanne (EPFL) have been using banana skins to develop a technique for locating, mapping, and killing cancer in the body. Their work focused on the black spots of an overripe banana, which they discovered to contain the same biomarkers as skin melanoma.
In mainstream practice, when a biopsy is conducted, dyes and fluorescent markers (or contrast agents) are used to color any suspicious areas. By comparison, the new electrochemical microscopy instrument uses eight soft micro-electrodes, lined side by side, that are brushed across potentially-cancerous tissue samples to trigger an electrochemical response in the body. The resulting electric currents from the action are then used by researchers to construct an image that will reveal any areas producing abnormal chemicals. As the Huffington Post writes, “It gives an idea of both the physical structure of the tissue and composition.”
According to Ecole Polytechnique Federale de Lausanne, the researchers found that the typical biomarkers of melanoma in humans can also be found in the black spots of overripe bananas. In a press statement, they note, “Taking advantage of this similarity, they [the researchers] were able to work on the fruit to develop an imaging technique capable of measuring tyrosinase in human skin and mapping out its distribution. An important step forward has also now been made in applying the imaging technique to thick tissues – like a biopsy of human skin – in addition to thin cross-sections of cells.”
In the future, the hope is the technique can be used to kill cancer cells during surgery. As Hubert Girault, head of the Laboratory of Physical and Analytical Electrochemistry at EPFLnotes in the study, they are “perfectly capable of using electrochemistry to kill cancer cells on microscope slides and in petri dishes, but doing so in thick tissue is another story.”
He sees a device with interconnected microelectrodes capable of generating an image that will reveal any tumors and then electrochemically destroy the cancerous cells found with a burst of voltage.“Around two volts, that’s not much, but it’s enough to generate oxygen radicals and eliminate cancer cells,” says Girault.
Via Huffington Post